Skin Moisturizers: Therapeutic Potential and Preventative Maintenance of Dry skin
Nalini Kaul, Michael Sinaisky and Elsie Kohoot, Hill Top Research, Poster No. P615, American Academy of Dermatology, (San Antonio, TX, February 2008).
ABSTRACT
Moisturizers are commonly used for skin smoothness and for breaking the cycle of dry skin. Often the importance of moisturizers is undermined by pharmaceutical products with "actives" gaining an upper hand. Moisturizers hydrate, smooth skin, and may also help improve barrier function in normal as well as diseased skin. Defective barrier function may trigger the development of atopic dermatitis or eczema. Besides locking in moisture specific ingredients like antioxidants, chelators and emulsifiers are being incorporated into moisturizers, to help boost the skin's natural defenses and restore a smooth appearance. Additionally these help improve dry irritated skin condition further. Moisturizer efficacy can be enhanced by choosing the right moisturizer for the targeted skin condition. As people seek preventative maintenance, new moisturizers with antioxidants and sun protection factors that serve to shield us from the effects of the environment are being developed. Our objective was to evaluate the therapeutic potential of a moisturizer and check for symptoms alleviation in very dry eczematous skin. M/F subjects who gave signed informed consent and met study criteria were enrolled in a clinical trial lasting several weeks. Evaluations included expert clinical visual assessments, subjective assessments and instruments. Results from our clinical test present the significant changes in xerosis, hydration, erythema, flaking, itching, scaling, observed with moisturization and restore confidence in their therapeutic potential. This may be a useful preventative maintenance measure in skin diseases.
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